The University of Chicago Header Logo

Search Result Details

Back to Search Results
This page shows the details of why an item matched the keywords from your search.
Search Results
Duan, Jubao
One or more keywords matched the following properties of Duan, Jubao
PropertyValue
overview Jubao Duan, PhD Charles R. Walgreen Research Chair Director, Stem Cell & Functional Genomics in Psychiatry Co-Director, Center for Psychiatric Genetics NorthShore University HealthSystem Research Institute Professor, Department of Psychiatry and Behavioral Neuroscience Contact Information 1001 University Place, Evanston, IL 60201 224.364.7564 224.364.7570 fax jduan@uchicago.edu; jduan@northshore.org Research Interests Molecular basis of schizophrenia and other neuropsychiatric and neurological disorders; Functional genetics and genomics; Disease modeling in human induced pluripotent stem cells (hiPSC)-derived neurons and brain organoids; Genome editing; Gene expression and regulation. Professional Services *Editorial Board Member: Complex Psychiatry; Frontiers in Neurogenomics; Scientific Reports *Ad hoc grant reviewer for MRC (Medical Research Council) of UK, Research Grant Council (RGC) of Hong Kong and other international agencies *2020 US VA Mental Hlth & Behav Sciences-A (MHBA) study section meeting *Ad hoc member of NIH study sections: IFCN-Z(57) and BDCN-W(06)M (2017); MDCN-P (57) (2016-2019); NINDS ZNS1 SRB-A (24) Special Emphasis Panel (LBD Center Without Walls (CWOW)) and IFCN-S (55) (2020); ZRG1 BCMB-A (51) R (Transformative R01 Program) (2020); NINDS ZNS1 SRB-S(03) U54 and GHD (2021)
One or more keywords matched the following items that are connected to Duan, Jubao
Item TypeName
Concept Binding Sites, Antibody
Concept Alleles
Concept Amino Acid Sequence
Concept Computer Simulation
Concept Antibody Specificity
Concept Base Sequence
Concept Complement System Proteins
Concept Cross-Sectional Studies
Concept Factor Analysis, Statistical
Concept Molecular Sequence Data
Concept Synaptic Transmission
Concept Nucleic Acid Conformation
Concept Major Histocompatibility Complex
Concept Sex Characteristics
Concept Nervous System
Concept Sweden
Concept Prader-Willi Syndrome
Concept Receptors, Serotonin
Concept Cohort Studies
Concept Regulatory Sequences, Nucleic Acid
Concept Smoking
Concept Schizophrenic Psychology
Concept Staphylococcal Infections
Concept Synapses
Concept Staphylococcal Protein A
Concept United States
Concept Angelman Syndrome
Concept Up-Regulation
Concept Rats, Sprague-Dawley
Concept Sequence Alignment
Concept Case-Control Studies
Concept Sequence Analysis, DNA
Concept Protein Structure, Tertiary
Concept Genes, Reporter
Concept Sepsis
Concept Methicillin-Resistant Staphylococcus aureus
Concept Genetic Association Studies
Concept GC Rich Sequence
Concept Exome
Concept Amino Acid Substitution
Concept Psychiatric Status Rating Scales
Concept Self-Assessment
Concept Severity of Illness Index
Concept Schizophrenia
Concept Staphylococcal Vaccines
Concept Staphylococcus
Concept Stress Disorders, Post-Traumatic
Concept Staphylococcus aureus
Concept Substrate Specificity
Concept Adaptor Proteins, Signal Transducing
Concept Regulatory Elements, Transcriptional
Concept Survival Analysis
Concept Open Reading Frames
Concept Mice, 129 Strain
Concept Genome, Human
Concept Surface Plasmon Resonance
Concept Repetitive Sequences, Amino Acid
Concept Williams Syndrome
Concept Receptor, Serotonin, 5-HT1B
Concept Tumor Suppressor Proteins
Concept Neural Stem Cells
Concept Transcriptome
Concept Genome-Wide Association Study
Concept RNA, Small Interfering
Concept Siblings
Concept Molecular Sequence Annotation
Concept Body Size
Concept Amyloid Precursor Protein Secretases
Concept Induced Pluripotent Stem Cells
Concept Epistasis, Genetic
Concept Follow-Up Studies
Concept Longitudinal Studies
Concept Retrospective Studies
Concept Signal Transduction
Concept Sequence Analysis, RNA
Concept Superantigens
Concept Polymorphism, Single Nucleotide
Concept RNA Stability
Concept Quantitative Trait Loci
Concept Genetic Loci
Academic Article DNA variation and psychopharmacology of the human serotonin receptor 1B (HTR1B) gene.
Academic Article Polymorphisms in the trace amine receptor 4 (TRAR4) gene on chromosome 6q23.2 are associated with susceptibility to schizophrenia.
Academic Article DTNBP1 (Dystrobrevin binding protein 1) and schizophrenia: association evidence in the 3' end of the gene.
Academic Article Neuregulin 1 (NRG1 ) and schizophrenia: analysis of a US family sample and the evidence in the balance.
Academic Article Mammalian mutation pressure, synonymous codon choice, and mRNA degradation.
Academic Article No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics.
Academic Article Identification of loci associated with schizophrenia by genome-wide association and follow-up.
Academic Article Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample.
Academic Article Genome-wide approaches to schizophrenia.
Academic Article Nontoxigenic protein A vaccine for methicillin-resistant Staphylococcus aureus infections in mice.
Academic Article Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
Academic Article Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications.
Academic Article Identifying protective antigens of Staphylococcus aureus, a pathogen that suppresses host immune responses.
Academic Article Genetic requirements for Staphylococcus aureus abscess formation and persistence in host tissues.
Academic Article Common variants on chromosome 6p22.1 are associated with schizophrenia.
Academic Article Preventing Staphylococcus aureus sepsis through the inhibition of its agglutination in blood.
Academic Article The role of genetics in the etiology of schizophrenia.
Academic Article The Internet-based MGS2 control sample: self report of mental illness.
Academic Article Protein A-specific monoclonal antibodies and prevention of Staphylococcus aureus disease in mice.
Academic Article Genome-wide association study of multiplex schizophrenia pedigrees.
Academic Article Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Academic Article Exploring Staphylococcus aureus pathways to disease for vaccine development.
Academic Article Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.
Academic Article Contribution of coagulases towards Staphylococcus aureus disease and protective immunity.
Academic Article Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.
Academic Article Abscess formation and alpha-hemolysin induced toxicity in a mouse model of Staphylococcus aureus peritoneal infection.
Academic Article Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor.
Academic Article Narcolepsy is strongly associated with the T-cell receptor alpha locus.
Academic Article IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge.
Academic Article Recurrent infections and immune evasion strategies of Staphylococcus aureus.
Academic Article ADAM10 mediates vascular injury induced by Staphylococcus aureus a-hemolysin.
Academic Article Genome-wide survey of interindividual differences of RNA stability in human lymphoblastoid cell lines.
Academic Article Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms.
Award or Honor Receipt NorthShore University HealthSystem Pilot Grant Award
Award or Honor Receipt NARSAD Elizabeth Elser Doolittle Investigator
Award or Honor Receipt NARSAD Young Investigator Award
Award or Honor Receipt NARSAD Young Investigator Award
Academic Article Reciprocal duplication of the Williams-Beuren syndrome deletion on chromosome 7q11.23 is associated with schizophrenia.
Academic Article Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases.
Academic Article Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
Academic Article A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder.
Academic Article Characterizing the genetic basis of methylome diversity in histologically normal human lung tissue.
Academic Article Transcriptome study of differential expression in schizophrenia.
Academic Article Biological insights from 108 schizophrenia-associated genetic loci.
Academic Article A sequence variant in human KALRN impairs protein function and coincides with reduced cortical thickness.
Academic Article Genome-wide association analysis identifies 13 new risk loci for schizophrenia.
Academic Article A common biological basis of obesity and nicotine addiction.
Academic Article MicroRNA-9 and microRNA-326 regulate human dopamine D2 receptor expression, and the microRNA-mediated expression regulation is altered by a genetic variant.
Academic Article Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs.
Academic Article Staphylococcus aureus infection induces protein A-mediated immune evasion in humans.
Academic Article Path from schizophrenia genomics to biology: gene regulation and perturbation in neurons derived from induced pluripotent stem cells and genome editing.
Academic Article Vaccine protection of leukopenic mice against Staphylococcus aureus bloodstream infection.
Academic Article Protein A-neutralizing monoclonal antibody protects neonatal mice against Staphylococcus aureus.
Academic Article Role of protein A in the evasion of host adaptive immune responses by Staphylococcus aureus.
Academic Article A monoclonal antibody that recognizes the E domain of staphylococcal protein A.
Academic Article N-acetylglucosaminylation of serine-aspartate repeat proteins promotes Staphylococcus aureus bloodstream infection.
Academic Article Mouse models for infectious diseases caused by Staphylococcus aureus.
Academic Article The capsular polysaccharide of Staphylococcus aureus is attached to peptidoglycan by the LytR-CpsA-Psr (LCP) family of enzymes.
Award or Honor Receipt Excellence in Research Award,Northshore University Healthsystem
Academic Article Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants.
Academic Article Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways.
Academic Article Staphylococcal manipulation of host immune responses.
Academic Article The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
Academic Article Antibodies against a secreted product of Staphylococcus aureus trigger phagocytic killing.
Academic Article New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.
Academic Article Parental Origin of Interstitial Duplications at 15q11.2-q13.3 in Schizophrenia and Neurodevelopmental Disorders.
Academic Article Peptidoglycan-linked protein A promotes T cell-dependent antibody expansion during Staphylococcus aureus infection.
Academic Article Reversal of dendritic phenotypes in 16p11.2 microduplication mouse model neurons by pharmacological targeting of a network hub.
Academic Article EssE Promotes Staphylococcus aureus ESS-Dependent Protein Secretion To Modify Host Immune Responses during Infection.
Academic Article Somatic Genomics and Clinical Features of Lung Adenocarcinoma: A Retrospective Study.
Academic Article Pathogenic conversion of coagulase-negative staphylococci.
Academic Article Winner's Curse Correction and Variable Thresholding Improve Performance of Polygenic Risk Modeling Based on Genome-Wide Association Study Summary-Level Data.
Award or Honor Receipt Special President’s Award,NorthShore University Healthsystem
Award or Honor Receipt Excellence in Research Award, NorthShore University Healthsystem
Academic Article Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci.
Academic Article Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects.
Academic Article Open chromatin dynamics reveals stage-specific transcriptional networks in hiPSC-based neurodevelopmental model.
Academic Article Transcriptional network analysis on brains reveals a potential regulatory role of PPP1R3F in autism spectrum disorders.
Academic Article Analysis of shared heritability in common disorders of the brain.
Academic Article Epigenome-wide analysis of DNA methylation in lung tissue shows concordance with blood studies and identifies tobacco smoke-inducible enhancers.
Academic Article Genome-Wide Association Study of Male Sexual Orientation.
Academic Article Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model.
Academic Article Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery.
Academic Article Deconvolution of transcriptional networks identifies TCF4 as a master regulator in schizophrenia.
Academic Article From Schizophrenia Genetics to Disease Biology: Harnessing New Concepts and Technologies.
Academic Article The Genetic Relevance of Human Induced Pluripotent Stem Cell-Derived Microglia to Alzheimer's Disease and Major Neuropsychiatric Disorders.
Academic Article Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants.
Academic Article Cell-Type-Specific Proteogenomic Signal Diffusion for Integrating Multi-Omics Data Predicts Novel Schizophrenia Risk Genes.
Academic Article CCmed: cross-condition mediation analysis for identifying replicable trans-associations mediated by cis-gene expression.
Academic Article Sex-specific nicotine sensitization and imprinting of self-administration in rats inform GWAS findings on human addiction phenotypes.
Academic Article A computational method for direct imputation of cell type-specific expression profiles and cellular compositions from bulk-tissue RNA-Seq in brain disorders.
Academic Article Cell type-specific and cross-population polygenic risk score analyses of MIR137 gene pathway in schizophrenia.
Academic Article Publicly Available hiPSC Lines with Extreme Polygenic Risk Scores for Modeling Schizophrenia.
Award or Honor Receipt Provost's Global Faculty Award
Academic Article Modeling common and rare genetic risk factors of neuropsychiatric disorders in human induced pluripotent stem cells.
Academic Article Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Academic Article Annotating functional effects of non-coding variants in neuropsychiatric cell types by deep transfer learning.
Academic Article BIN1 is a key regulator of proinflammatory and neurodegeneration-related activation in microglia.
Academic Article Loss of function of OTUD7A in the schizophrenia- associated 15q13.3 deletion impairs synapse development and function in human neurons.
Academic Article Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell-Derived Neurons.
Academic Article Modeling PTSD neuronal stress responses in a dish.
Concept Autism Spectrum Disorder
Academic Article Multiple genes in a single GWAS risk locus synergistically mediate aberrant synaptic development and function in human neurons.
Academic Article Potential diagnostic biomarkers for schizophrenia.
Academic Article Human stem cell modeling of neuropsychiatric disorders: from polygenicity to convergence.
Academic Article Scaled and Efficient Derivation of Loss of Function Alleles in Risk Genes for Neurodevelopmental and Psychiatric Disorders in Human iPSC.
Search Criteria
  • National Institute of Neurological Disorders and Stroke
  • U
  • S